GEO series
Sexually dimorphic effects of ADNP mutation and Davunotide treatment on mice hippocampal transcriptome
GSE272331
Mus musculus
Expression profiling by high throughput sequencing
25 samples
2025/05/30
GPL19057
Summary
ADNP haplo-insufficient (Adnp +/- ) mice or CRSIPR/Cas9 edited to carry the most prevalent neurodevelopmental ADNP syndrome mutation, p.Tyr718*. A subgroup was treated the ADNP fragment, investigational drug, NAP (davunetide).
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Paper (PMID 39715923) ↗
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