← BioTransfer GEO Dataset Finder
GEO series

ST2+ T-regulatory Cells in Renal Inflammation and Fibrosis following Ischemic Kidney Injury

GSE272380 Mus musculus Expression profiling by high throughput sequencing 5 samples Submitted 2024/08/27 Platform GPL30172
Summary
The role of IL-33 and its receptor ST2 in kidney injury is not well understood. This study demonstrates the importance of ST2 expression on the T-regulatory cells (Tregs) for the resolution of renal injury by suppressing inflammation and fibrosis. Treg-specific deletion of ST2, detrimentally impacted late outcomes of renal injury worsening the impairment of kidney function, inflammation, and fibrosis.
Published in
ST2 + T-Regulatory Cells in Renal Inflammation and Fibrosis after Ischemic Kidney Injury
Sabapathy V, Price A, Cheru NT et al. · Journal of the American Society of Nephrology : JASN 2025 · PMID 39186386 · doi:10.1681/ASN.0000000000000471
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE272380_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 5 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1136539 and SRA study SRP520301. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 5 more — browse all 5 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.