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RNA-seq analysis further corroborated the reversal effect of asp on AOA-enhanced ISG expression in L929 cells

GSE272896 Mus musculus Expression profiling by high throughput sequencing 12 samples 2025/12/31 GPL17021
Summary
To assess the functional significance of asp in the cGAS-STING pathway, these two metabolites were individually added along with AOA to the culture medium, followed by HT-DNA stimulation for 6 hours. Interestingly, asp fully reversed the amplification effect of A on STING-mediated immune response
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