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Expression changes in mouse proximal tubules during primary culture

GSE273058 Mus musculus Expression profiling by high throughput sequencing 18 samples 2024/09/17 GPL24247
Summary
Primary cultures of proximal tubule cells are widely used to model the behavior of kidney epithelial cells in vitro. De-differentiation of primary cells upon culture has been observed and appreciated for decades, yet the mechanisms driving this phenomenon remain poorly understood. The goal of this experiment was to quantitatively measure the changes in expression of purified proximal tubules as they enter primary culture.
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NCBI GEO page ↗ Paper (PMID 39358473) ↗ {# Names what the click gives you. "Open in finder" meant nothing to a visitor who arrived from a search engine and has never seen the tool. #} Find more mouse RNA-seq datasets →
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