Multi-omics Analysis of Umbilical Cord Hematopoietic Stem Cells from a Multi-ethnic Cohort of Hawaii Reveals the Intergenerational Effect of Maternal Pre-Pregnancy Obesity and Risk Prediction for Cancers
DNA methylation · human · 122 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Homo sapiens (human)
- Samples
- 122 samples: 73 distinct titles, 1 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
- Paper
- Multiomics analysis of umbilical cord hematopoietic stem cells from a multiethnic cohort of Hawaii reveals the intergenerational effect of maternal prepregnancy obesity and risks for cancersGigaScience · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE273075_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA1139938 and SRA study SRP521961. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 122 sample titles: 73 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8415937 MT11
- GSM8415938 MT12
- GSM8415939 MT14
- GSM8415940 MT16
- GSM8415941 MT18
- GSM8415942 MT20
- GSM8415943 MT25
- GSM8415944 MT26
- GSM8415945 MT27
- GSM8415946 MT28
- GSM8415947 MT30
- GSM8415948 MT31
- GSM8415949 MT32
- GSM8415950 MT33
- GSM8415951 MT34
- GSM8415952 MT35
- GSM8415953 MT36
- GSM8415954 MT37
- GSM8415955 MT38
- GSM8415956 MT39
- GSM8415957 MT40
- GSM8415958 MT41
- GSM8415959 MT42
- GSM8415960 MT43
- GSM8415961 MT45
- GSM8415962 MT46
- GSM8415963 MT47
- GSM8415964 MT48
- GSM8415965 MT50
- GSM8415966 MT51
- GSM8415967 MT53
- GSM8415968 MT55
- GSM8415969 MT56
- GSM8415970 MT57
- GSM8415971 MT58
- GSM8415972 MT59
- GSM8415973 MT63
- GSM8415974 MT65
- GSM8415975 MT66
- GSM8415976 MT67
+ 82 more — browse all 122 samples with per-sample file links →
- GSE272978 Multi-omics Analysis of Umbilical Cord Hematopoietic Stem Cells from a Multi-ethnic Cohort of Hawaii Reveals the Intergenerational Effect of Maternal Pre-Pregnancy Obesity and Risk Prediction for Cancers 50 samples shares intergenerational, hematopoietic, pre-pregnancy, multi-ethnic, multi-omics, prediction, umbilical, maternal
- GSE289648 Maternal acute SARS-CoV-2 infection impairs preimplantation embryo development and reprograms early offspring hematopoietic system 102 samples shares hematopoietic, maternal
- GSE75478 Single-cell indexed RNA-Seq of human hematopoietic stem and progenitors 2414 samples shares hematopoietic
- GSE24505 Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation 757 samples shares hematopoietic
- GSE285943 A reference model for circulating hematopoietic stem cells with applications to diagnostics 299 samples shares hematopoietic
- GSE30377 Human Hematopoietic and Leukemic Stem Cell Gene Expression Profiles 117 samples shares hematopoietic
- GSE233478 RNA-seq profiling of human hematopoietic cell populations across development. 106 samples shares hematopoietic
- GSE303350 JARID2 Inhibition Reprograms Human Hematopoietic Progenitor Cells To Enhance Bone Marrow Transplantation 88 samples shares hematopoietic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.