GEO series
Peripheral nerve injury induces dystonia-like movements and dysregulation in the energy metabolism: A multi-omics descriptive study in Thap1+/− mice
GSE273220
Mus musculus
Expression profiling by high throughput sequencing
72 samples
2025/01/03
GPL30172
Summary
To elicit a dystonia-like phenotype in a genetically predisposed DYT-THAP1 mouse model (Thap1+/-) by performing a right sciatic nerve crush injury. To identify novel pathophysiological pathways and possible biomarker, we performed a multi-omic analysis of three dystonia-relevant brain regions
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Paper (PMID 39732371) ↗
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