Behavioral, Neurotransmitter and Transcriptomic Analyses in male and female Fmr1 Knockout Mice
RNA-seq (gene expression) · mouse · 15 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 15 samples: 4 × Wild type, male, vs 4 × Wild type, female, vs 4 × Fmr1 knock out, female, vs 3 × Fmr1 knock out, male,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Behavioral, neurotransmitter and transcriptomic analyses in male and female Fmr1 KO miceFrontiers in behavioral neuroscience · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE275170_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1149741 and SRA study SRP527327. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 15 samples.
How we read this: 4 replicated groups read from 15 sample titles; they account for 15 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8472306 Wild type, male, 1 Wild type, male,
- GSM8472307 Wild type, male, 2 Wild type, male,
- GSM8472308 Wild type, male, 3 Wild type, male,
- GSM8472309 Wild type, male, 4 Wild type, male,
- GSM8472310 Wild type, female, 1 Wild type, female,
- GSM8472311 Wild type, female, 2 Wild type, female,
- GSM8472312 Wild type, female, 3 Wild type, female,
- GSM8472313 Wild type, female, 4 Wild type, female,
- GSM8472314 Fmr1 knock out, male, 1 Fmr1 knock out, male,
- GSM8472315 Fmr1 knock out, male, 3 Fmr1 knock out, male,
- GSM8472316 Fmr1 knock out, male, 4 Fmr1 knock out, male,
- GSM8472317 Fmr1 knock out, female, 1 Fmr1 knock out, female,
- GSM8472318 Fmr1 knock out, female, 2 Fmr1 knock out, female,
- GSM8472319 Fmr1 knock out, female, 3 Fmr1 knock out, female,
- GSM8472320 Fmr1 knock out, female, 4 Fmr1 knock out, female,
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.