GEO series
Targeting heterogeneous tumor microenvironments in pancreatic cancer mouse models of metastasis by TGFB depletion
GSE275596
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2024/08/27
GPL24247
Summary
The dual tumor-suppressive and promoting function of TGFB signaling has made its targeting challenging. We hereby examined the effects of TGFB depletion by AVID200/BMS-986416(TGFB-TRAP), a TGFB ligand trap, on the tumor microenvironment of pancreatic ductal adenocarcinoma (PDAC) murine models with different organ-specific metastasis using single-nuclear RNA-sequencing (snRNA-seq)
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