BDGR-49 protects BALB/c mice from lethal, intranasal challenge of Venezuelan Equine Encephalitis Virus
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 6 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The antiviral BDGR-49 provides protection from lethal, neurotropic Venezuelan equine encephalitis virus intranasal infection in miceJournal of virology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE277300_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1161688 and SRA study SRP533001. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 24 samples.
How we read this: 6 replicated groups read from 24 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8518283 VEEV, 2dpi, 0mkd, Rep1 VEEV, 2dpi, 0mkd,
- GSM8518284 VEEV, 2dpi, 0mkd, Rep2 VEEV, 2dpi, 0mkd,
- GSM8518285 VEEV, 2dpi, 0mkd, Rep3 VEEV, 2dpi, 0mkd,
- GSM8518286 VEEV, 2dpi, 0mkd, Rep4 VEEV, 2dpi, 0mkd,
- GSM8518287 VEEV, 4dpi, 0mkd, Rep1 VEEV, 4dpi, 0mkd,
- GSM8518288 VEEV, 4dpi, 0mkd, Rep2 VEEV, 4dpi, 0mkd,
- GSM8518289 VEEV, 4dpi, 0mkd, Rep3 VEEV, 4dpi, 0mkd,
- GSM8518290 VEEV, 4dpi, 0mkd, Rep4 VEEV, 4dpi, 0mkd,
- GSM8518291 VEEV, 5dpi, 0mkd, Rep1 VEEV, 5dpi, 0mkd,
- GSM8518292 VEEV, 5dpi, 0mkd, Rep2 VEEV, 5dpi, 0mkd,
- GSM8518293 VEEV, 5dpi, 0mkd, Rep3 VEEV, 5dpi, 0mkd,
- GSM8518294 VEEV, 5dpi, 0mkd, Rep4 VEEV, 5dpi, 0mkd,
- GSM8518295 VEEV, 2dpi, 12mkd, Rep1 VEEV, 2dpi, 12mkd,
- GSM8518296 VEEV, 2dpi, 12mkd, Rep2 VEEV, 2dpi, 12mkd,
- GSM8518297 VEEV, 2dpi, 12mkd, Rep3 VEEV, 2dpi, 12mkd,
- GSM8518298 VEEV, 2dpi, 12mkd, Rep4 VEEV, 2dpi, 12mkd,
- GSM8518299 VEEV, 4dpi, 12mkd, Rep1 VEEV, 4dpi, 12mkd,
- GSM8518300 VEEV, 4dpi, 12mkd, Rep2 VEEV, 4dpi, 12mkd,
- GSM8518301 VEEV, 4dpi, 12mkd, Rep3 VEEV, 4dpi, 12mkd,
- GSM8518302 VEEV, 4dpi, 12mkd, Rep4 VEEV, 4dpi, 12mkd,
- GSM8518303 VEEV, 8dpi, 12mkd, Rep1 VEEV, 8dpi, 12mkd,
- GSM8518304 VEEV, 8dpi, 12mkd, Rep2 VEEV, 8dpi, 12mkd,
- GSM8518305 VEEV, 8dpi, 12mkd, Rep3 VEEV, 8dpi, 12mkd,
- GSM8518306 VEEV, 8dpi, 12mkd, Rep4 VEEV, 8dpi, 12mkd,
- GSE277431 Suboptimal prophylactic treatments with BDGR-49 in a lethal VEEV TC-83 mouse model 16 samples shares bdgr-49, lethal
- GSE324524 Identification of host lncRNAs that impact Venezuelan equine encephalitis virus replication 39 samples shares encephalitis, venezuelan
- GSE324479 Identification of host lncRNAs that impact Venezuelan equine encephalitis virus replication 36 samples shares encephalitis, venezuelan
- GSE274566 Single-cell transcriptomic profiling of brain immune infiltration following Venezuelan equine encephalitis virus infection 6 samples shares encephalitis, venezuelan
- GSE274057 Whole transcriptome sequencing for upper tract urothelial carcinoma (UTUC) of BALB/c female mice treated with N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) 37 samples shares balb
- GSE226608 Balb/c mouse lung tissue RNA-Seq in mouse OVA asthma model with and without anti-mouse-IL-4Ra antibody treatment. 15 samples shares balb
- GSE330744 Differential physiological, behavioral, and medial prefrontal cortex transcriptomic responses to chronic restraint stress between BALB/c and C57BL/6J mice 12 samples shares balb
- GSE320498 Glomerulus-enriched RNA-seq of BALB/cAjcl and BALB/cByJcl mice at baseline and Day 5 after Adriamycin administration 12 samples shares balb
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.