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Hepatic miR-93 promotes the pathogenesis of metabolic dysfunction-associated steatotic liver disease by suppressing SIRT1

GSE277560 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2025/04/14 Platform GPL24247
Summary
The molecular mechanisms underlying the pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD) remain largely unclear. Emerging evidence suggests that microRNAs (miRNAs) play a critical role in transcriptional regulation by targeting genes involved in MASLD and other metabolic disorders, this study aims to elucidate the role of miR-93 in lipid metabolism and its impact on MASLD progression.
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Direct links to NCBI, no account and no request form: the whole study as GSE277560_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1162804 and SRA study SRP533598. Searching any of these in the dataset finder brings you back here.

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