GEO series
LncRNA H19 exacerbates hepatic inflammation and oxidative stress in alcohol-related liver disease by sponging miR-22 to derepress SIRT1
GSE315288
Mus musculus
Expression profiling by high throughput sequencing
8 samples
2026/06/30
GPL24247
Summary
LncRNA H19 is upregulated in various liver diseases and promotes steatosis and inflammation, but its role and mechanism in alcohol-related liver disease (ALD) remain unclear. This study aimed to investigate whether H19 exacerbates ALD via the microRNA-22 (miR-22)/Sirtuin1 (SIRT1) axis.
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