IL27 as a Novel Biomarker for Pruritus Specific in Nodular Prurigo and Bullous Pemphigoid
RNA-seq (gene expression) · human · 23 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 23 samples: 9 × PN vs 8 × control vs 6 × BPGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- IL-27 as a novel biomarker for pruritus in nodular prurigo and bullous pemphigoidFrontiers in immunology · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE278382_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1166908 and SRA study SRP535611. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 23 samples.
How we read this: 3 replicated groups read from 23 sample titles; they account for 23 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8545678 BP1 BP
- GSM8545679 BP2 BP
- GSM8545680 BP3 BP
- GSM8545681 BP4 BP
- GSM8545682 BP5 BP
- GSM8545683 BP6 BP
- GSM8545684 control1 control
- GSM8545685 control2 control
- GSM8545686 control3 control
- GSM8545687 control4 control
- GSM8545688 control5 control
- GSM8545689 control6 control
- GSM8545690 control7 control
- GSM8545691 control8 control
- GSM8545692 PN1 PN
- GSM8545693 PN2 PN
- GSM8545694 PN3 PN
- GSM8545695 PN4 PN
- GSM8545696 PN5 PN
- GSM8545697 PN6 PN
- GSM8545698 PN7 PN
- GSM8545699 PN8 PN
- GSM8545700 PN9 PN
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.