Lysine acetylation of aquaporin-3 promotes water reabsorption but is not essential for urine concentration
RNA-seq (gene expression) · mouse · 28 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 28 samples: 6 conditions, mostly with about 5 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Lysine acetylation of aquaporin-3 promotes water permeability but is not essential for urine concentrating abilityAmerican journal of physiology. Renal physiology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE279083_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1170319 and SRA study SRP537218. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 28 samples.
How we read this: 6 replicated groups read from 28 sample titles; they account for 28 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8561058 Male WT1 Male WT
- GSM8561059 Male R1 Male
- GSM8561060 Male Q1 Male Q
- GSM8561061 Female WT1 Female WT
- GSM8561062 Female WT2 Female WT
- GSM8561063 Female R1 Female
- GSM8561064 Female Q1 Female Q
- GSM8561065 Male WT2 Male WT
- GSM8561066 Male R2 Male
- GSM8561067 Male Q2 Male Q
- GSM8561068 Female WT3 Female WT
- GSM8561069 Female WT4 Female WT
- GSM8561070 Female R2 Female
- GSM8561071 Female Q2 Female Q
- GSM8561072 Male WT3 Male WT
- GSM8561073 Male R3 Male
- GSM8561074 Male Q3 Male Q
- GSM8561075 Female R3 Female
- GSM8561076 Female Q3 Female Q
- GSM8561077 Male WT4 Male WT
- GSM8561078 Male R4 Male
- GSM8561079 Male Q4 Male Q
- GSM8561080 Female Q4 Female Q
- GSM8561081 Male WT5 Male WT
- GSM8561082 Male R5 Male
- GSM8561083 Male Q5 Male Q
- GSM8561084 Female WT5 Female WT
- GSM8561085 Female Q5 Female Q
- GSE306911 Chronic exposure of PFOS at environmental-relevant concentration promotes TNBC aggressive phenotypes 6 samples shares concentration, promotes
- GSE317859 Effect of PPARγ2 acetylation in at lysine 382 in mouse beige adipocyte differentiation 6 samples shares acetylation, lysine
- GSE226831 Metformin Promotes Proliferation of Mouse Female Germline Stem Cells by Histone Acetylation Modification of Traf2 12 samples shares acetylation, promotes
- GSE306009 ACLY-driven metabolic reprogramming promotes histone acetylation and inflammation-associated fibrosis in chronic kidney disease 6 samples shares acetylation, promotes
- GSE280488 A histone hyperacetylation pulse induces cellular memory of gene expression and 3-dimensional genome folding [RNA-seq] 114 samples shares acetylation
- GSE173532 Altering metabolism to program cell identity via NAD+ dependent deacetylation [RNA-seq] 30 samples shares acetylation
- GSE284312 Transfer RNA acetylation regulates in vivo mammalian stress signaling [tissues] 24 samples shares acetylation
- GSE280522 p300/CBP-catalyzed acetylation safeguards minor zygotic genome activation via activating DUX [RNA-Seq] 24 samples shares acetylation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.