GEO series
DYRK1A Inhibition via Conditional Knockout
GSE279317
Mus musculus
Expression profiling by high throughput sequencing
16 samples
2025/05/02
GPL30172
Summary
Chemical inhibition of DYRK1A (e.g. using harmine) inhibits Th17 and promotes Treg differentiation. To better understand the mechanisms by which DYRK1A regulates Th17 differentiation, we are comparing expression profiles of naïve CD4+ T cells during the course of Th17 differentiation in the presence or absence of harmine.
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Paper (PMID 39846842) ↗
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