Impact of Early Bisphenol A Exposure on Transcriptome and Chromatin Accessibility in Brain Oligodendrocytes of Juvenile Mice [ATAC-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 19 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 19 samples: 5 × O4, male, control, ATAC, vs 5 × O4, male, BPA, ATAC, vs 5 × O4, female, BPA, ATAC, vs 4 × O4, female, control, ATAC,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Bisphenol A exposure during gestation and lactation in mice: Sex-specific consequences on oligodendrocytes and myelinationToxicology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE280169_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1176689 and SRA study SRP540468. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 19 samples.
How we read this: 4 replicated groups read from 19 sample titles; they account for 19 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8591074 O4, male, control, ATAC, rep1 O4, male, control, ATAC,
- GSM8591075 O4, male, control, ATAC, rep2 O4, male, control, ATAC,
- GSM8591076 O4, male, control, ATAC, rep3 O4, male, control, ATAC,
- GSM8591077 O4, male, control, ATAC, rep4 O4, male, control, ATAC,
- GSM8591078 O4, male, control, ATAC, rep5 O4, male, control, ATAC,
- GSM8591079 O4, female, control, ATAC, rep1 O4, female, control, AT…
- GSM8591080 O4, female, control, ATAC, rep2 O4, female, control, AT…
- GSM8591081 O4, female, control, ATAC, rep3 O4, female, control, AT…
- GSM8591082 O4, female, control, ATAC, rep4 O4, female, control, AT…
- GSM8591083 O4, male, BPA, ATAC, rep1 O4, male, BPA, ATAC,
- GSM8591084 O4, male, BPA, ATAC, rep2 O4, male, BPA, ATAC,
- GSM8591085 O4, male, BPA, ATAC, rep3 O4, male, BPA, ATAC,
- GSM8591086 O4, male, BPA, ATAC, rep4 O4, male, BPA, ATAC,
- GSM8591087 O4, male, BPA, ATAC, rep5 O4, male, BPA, ATAC,
- GSM8591088 O4, female, BPA, ATAC, rep1 O4, female, BPA, ATAC,
- GSM8591089 O4, female, BPA, ATAC, rep2 O4, female, BPA, ATAC,
- GSM8591090 O4, female, BPA, ATAC, rep3 O4, female, BPA, ATAC,
- GSM8591091 O4, female, BPA, ATAC, rep4 O4, female, BPA, ATAC,
- GSM8591092 O4, female, BPA, ATAC, rep5 O4, female, BPA, ATAC,
- GSE264229 Mapping the male mouse chromatin accessibility landscape by UUATAC-seq 33 samples shares accessibility, chromatin, atac-seq
- GSE249077 Mapping the female mouse chromatin accessibility landscape by UUATAC-seq 23 samples shares accessibility, chromatin, atac-seq
- GSE342565 Chromatin accessibility profiling of high endothelial cells (HECs) from mouse peripheral lymph node and Peyer's patch by ATAC-seq 2 samples shares accessibility, chromatin, atac-seq
- GSE283483 Novel environment exposure drives temporally defined and region-specific chromatin accessibility and gene expression programs in the hippocampus 160 samples shares accessibility, chromatin, exposure
- GSE216371 A single-cell atlas of chromatin accessibility in mouse organogenesis 68 samples shares accessibility, chromatin
- GSE294103 SIRT6 Overexpression Counteracts Chromatin Aging [ATAC-Seq_tg] 28 samples shares chromatin, atac-seq
- GSE246986 Ki67-mediated chromatin accessibility impedes B-cell antigen-receptor gene rearrangement 24 samples shares accessibility, chromatin
- GSE249834 Impact of Chromatin Immunoprecipitation Crosslinking Conditions on Selective Genomic Interactions by NF‐κB Family Members 21 samples shares chromatin, impact
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.