← BioTransfer GEO Dataset Finder
GEO series

Transcriptional analysis on ischemia-reperfusion injury of mouse normal or steatotic livers

GSE280421 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/12/04 Platform GPL28330
Summary
Hexokinase is a key enzyme in the glycolytic pathway, but its role in RIPK1-mediated apoptosis is not clear. We therefore treated MEFs with sicontrol as well as siHK2 and performed RNA-seq
Published in
A glucose kinase-independent HK2 activity prevents TNF-induced cell death by phosphorylating RIPK1
Zou T, Liu R, Wang G et al. · Nature communications 2025 · PMID 41233370 · doi:10.1038/s41467-025-64939-1
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE280421_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1178563 and SRA study SRP541534. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.