Integrin αV as a potential target in aortic aneurysm and dissection II
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Integrin αV emerges as a potential therapeutic target with cautionary implications in thoracic aortic aneurysm and dissectionThe Journal of thoracic and cardiovascular surgery · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE280456_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1178646 and SRA study SRP541615. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 18 more — browse all 18 samples with per-sample file links →
- GSE263304 Integrin αV as a potential target in aortic aneurysm and dissection 14 samples shares dissection, potential, integrin, aneurysm, target, aortic
- GSE298176 CTHRC1 is a new therapeutic target and serum diagnostic biomarker for aortic dissection 54 samples shares dissection, target, aortic
- GSE309042 S100A4-lineage Cells Contribute Modesty to Angiotensin II-mediated Thoracic Aortic Aneurysms Through Angiotensin II Type 1a Receptor in Mice 86 samples shares aneurysm, aortic
- GSE325608 Transcriptome Sequencing of BAPN-Induced Aortic Dissection in Male and Female Mice 48 samples shares dissection, aortic
- GSE329337 ATAD3A Limits Aortic Dissection via Mito-Lysosome Contacts and Lipoylation 24 samples shares dissection, aortic
- GSE234086 The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy 24 samples shares potential, target
- GSE261845 Targeting melanoma cell-intrinsic beta2 integrin inhibits ICAM-1-mediated tumor progression 20 samples shares integrin, target
- GSE252789 Multi-omics based dynamic molecular changes characterization in EV-A71-infected mice elucidating potential therapeutic targets 20 samples shares potential, target
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.