Polycomb Repressive Complex 1 Primes Non-Growing Oocytes for Growth and Early Embryogenesis [RNA-Seq]
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 6 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Polycomb Repressive Complex 1 primes non-growing oocytes for growth and early embryogenesisCell research · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE280638_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1179867 and SRA study SRP541980. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 6 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8602744 RNAseq_PRC2ctrl_P6NGO_rep1 RNAseq_PRC2ctrl_P6NGO
- GSM8602746 RNAseq_PRC2ctrl_P6NGO_rep2 RNAseq_PRC2ctrl_P6NGO
- GSM8602748 RNAseq_PRC2cKO_P6NGO_rep1 RNAseq_PRC2cKO_P6NGO
- GSM8602749 RNAseq_PRC2cKO_P6NGO_rep2 RNAseq_PRC2cKO_P6NGO
- GSM8602751 RNAseq_PRC2ctrl_P7GO_rep1 RNAseq_PRC2ctrl_P7GO
- GSM8602753 RNAseq_PRC2ctrl_P7GO_rep2 RNAseq_PRC2ctrl_P7GO
- GSM8602754 RNAseq_PRC2cKO_P7GO_rep1 RNAseq_PRC2cKO_P7GO
- GSM8602756 RNAseq_PRC2cKO_P7GO_rep2 RNAseq_PRC2cKO_P7GO
- GSM9327826 RNAseq_PRC1ctrl_P7GO_rep1 RNAseq_PRC1ctrl_P7GO
- GSM9327827 RNAseq_PRC1ctrl_P7GO_rep2 RNAseq_PRC1ctrl_P7GO
- GSM9327828 RNAseq_PRC1cKO_P7GO_rep1 RNAseq_PRC1cKO_P7GO
- GSM9327829 RNAseq_PRC1cKO_P7GO_rep2 RNAseq_PRC1cKO_P7GO
- GSE311349 Polycomb Repressive Complex 1 Primes Non-Growing Oocytes for Growth and Early Embryogenesis [CUT&Tag] 32 samples shares embryogenesis, non-growing, repressive, polycomb, complex, oocytes, primes
- GSE302804 Polycomb Repressive-Deubiquitinase Complex Safeguards Oocyte Epigenome and Female Fertility by Restraining Polycomb Activity [RNA-Seq] 37 samples shares repressive, polycomb, complex, rna-seq
- GSE289248 Crosstalk between the polycomb repressive complex 2 and DNA methylation mediates neuroendocrine prostate cancer lineage plasticity [RNA-Seq] 2 samples shares repressive, polycomb, complex, rna-seq
- GSE299584 Correlated protein-RNA associations and a requirement for HNRNPU in the long-range recruitment of Polycomb Repressive Complexes by the lncRNAs Airn and Kcnq1ot1 20 samples shares repressive, polycomb, complex
- GSE286287 Unbalanced chromatin binding of Polycomb complexes drives neurodevelopmental disorders [RNA-Seq] 18 samples shares polycomb, complex, rna-seq
- GSE286294 Unbalanced chromatin binding of Polycomb complexes drives neurodevelopmental disorders [scRNA-Seq] 6 samples shares polycomb, complex, rna-seq
- GSE299587 Correlated protein-RNA associations and a requirement for HNRNPU in the long-range recruitment of Polycomb Repressive Complexes by the lncRNAs Airn and Kcnq1ot1 PLOS Genetics 40 samples shares repressive, polycomb, complex
- GSE216807 Polycomb Repressive Complexes occupancy reveals PRC2- independent PRC1 critical role in the control of limb development [ChIP-seq] 19 samples shares repressive, polycomb, complex
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.