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Transcriptional profiling of aged and young mouse hearts

GSE281775 Mus musculus Expression profiling by high throughput sequencing 9 samples Submitted 2025/11/11 Platform GPL24247
Summary
We identified Dnmt3a and Esrrg as the putative regulators of CM aging. Here, we overexpressed Esrrg, Dnmt3a and control GFP proteins in adult hearts and performed bulk RNA-seq to discover molecular pathways associated with these proteins.
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Direct links to NCBI, no account and no request form: the whole study as GSE281775_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1185692 and SRA study SRP544956. Searching any of these in the dataset finder brings you back here.

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