Changes of gene expression in DRG tissue after pathologic pain
RNA-seq (gene expression) · mouse · 15 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 15 samples: 5 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Histone lactylation regulates DOCK4 to control heat nociception and supports Dynein-mediated Nav1.7 traffickingNature communications · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE283287_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1193045 and SRA study SRP548681. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 15 samples.
How we read this: 5 replicated groups read from 15 sample titles; they account for 15 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8659433 Naïve-rep 1 Naïve
- GSM8659434 Naïve-rep 2 Naïve
- GSM8659435 Naïve-rep 3 Naïve
- GSM8659436 CFA-rep 1 CFA
- GSM8659437 CFA-rep 2 CFA
- GSM8659438 CFA-rep 3 CFA
- GSM8659439 LLC-rep 1 LLC
- GSM8659440 LLC-rep 2 LLC
- GSM8659441 LLC-rep 3 LLC
- GSM8659442 PTX-rep 1 PTX
- GSM8659443 PTX-rep 2 PTX
- GSM8659444 PTX-rep 3 PTX
- GSM8659445 SNL-rep 1 SNL
- GSM8659446 SNL-rep 2 SNL
- GSM8659447 SNL-rep 3 SNL
- GSE327205 RNA-seq analysis of dorsal root ganglia (DRG) from MIA-induced osteoarthritis mice with acupuncture or no treatment: Focus on neuro-immune crosstalk genes 8 samples shares drg
- GSE330238 Bulk RNA-seq of dorsal root ganglion (DRG) neuron with 3 conditions 9 samples shares drg
- GSE279813 Gene expression changes in skin of dihydrotestosterone-induced mice after treatment of a newly-developed traditional Chinese medicine formula, Hanlianxiang. 24 samples shares changes
- GSE186037 Gene expression changes in mouse kidney cancer cells (RENCA) after anti-PD-L1 resistance 12 samples shares changes
- GSE301321 DRG tissue CSDE1-IP sequencing using sciatic nerve injured and uninjured mice. 12 samples shares drg
- GSE301319 DRG tissue RiboTag and bulk RNA sequencing using sciatic nerve injured and uninjured mice. 12 samples shares drg
- GSE196234 Sensory neuron gene expression changes in response to type 2 skin inflammation after recovery 10 samples shares changes
- GSE249687 Three-dimensional chromatin architecture in DRG neurons following sciatic nerve injury in WT and Rad21 KO mice. 52 samples shares drg
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.