Transfer RNA acetylation regulates in vivo mammalian stress signaling
RNA-seq (gene expression) · mouse · 30 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 30 samples: 8 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transfer RNA acetylation regulates in vivo mammalian stress signalingScience advances · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE284313_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1198505 and SRA study SRP551541. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 15 samples read as cases, 15 as controls.
How we read this: 8 replicated groups read from 30 sample titles; they account for 30 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8682171 Thumpd Wildtype Replicate 1 Thumpd Wildtype
- GSM8682172 Thumpd Wildtype Replicate 2 Thumpd Wildtype
- GSM8682173 Thumpd Wildtype Replicate 3 Thumpd Wildtype
- GSM8682174 Thumpd Knockout Replicate 1 Thumpd Knockout
- GSM8682175 Thumpd Knockout Replicate 2 Thumpd Knockout
- GSM8682176 Thumpd Knockout Replicate 3 Thumpd Knockout
- GSM8682186 Liver Wildtype Replicate 1 Liver Wildtype
- GSM8682187 Liver Wildtype Replicate 2 Liver Wildtype
- GSM8682188 Liver Wildtype Replicate 3 Liver Wildtype
- GSM8682189 Liver Wildtype Replicate 4 Liver Wildtype
- GSM8682190 Liver Knockout Replicate 5 Liver Knockout
- GSM8682191 Liver Knockout Replicate 6 Liver Knockout
- GSM8682192 Liver Knockout Replicate 7 Liver Knockout
- GSM8682193 Liver Knockout Replicate 8 Liver Knockout
- GSM8682194 Cerebellum Wildtype Replicate 1 Cerebellum Wildtype
- GSM8682195 Cerebellum Wildtype Replicate 2 Cerebellum Wildtype
- GSM8682196 Cerebellum Wildtype Replicate 3 Cerebellum Wildtype
- GSM8682197 Cerebellum Wildtype Replicate 4 Cerebellum Wildtype
- GSM8682198 Cerebellum Knockout Replicate 5 Cerebellum Knockout
- GSM8682199 Cerebellum Knockout Replicate 6 Cerebellum Knockout
- GSM8682200 Cerebellum Knockout Replicate 7 Cerebellum Knockout
- GSM8682201 Cerebellum Knockout Replicate 8 Cerebellum Knockout
- GSM8682202 Testes Wildtype Replicate 1 Testes Wildtype
- GSM8682203 Testes Wildtype Replicate 2 Testes Wildtype
- GSM8682204 Testes Wildtype Replicate 3 Testes Wildtype
- GSM8682205 Testes Wildtype Replicate 4 Testes Wildtype
- GSM8682206 Testes Knockout Replicate 5 Testes Knockout
- GSM8682207 Testes Knockout Replicate 6 Testes Knockout
- GSM8682208 Testes Knockout Replicate 7 Testes Knockout
- GSM8682209 Testes Knockout Replicate 8 Testes Knockout
- GSE264571 Latent Epigenetic Programs in Müller Glia Contribute to Stress, Injury, and Disease Response in the Retina 87 samples shares stress
- GSE270550 Mutant CEBPA promotes tolerance to inflammatory stress through deficient AP-1 activation [RNA-Seq] 75 samples shares stress
- GSE300603 Fetal reversion from diverse lineages sustains the intestinal stem cell pool and confers stress resilience. 34 samples shares stress
- GSE285529 CD133+PD-L1+ cancer cells confer resistance to adoptively transferred engineered macrophage-based therapy in melanoma. 30 samples shares transfer
- GSE268901 Heterochromatin Protein ERH represses alternative cell fates during early mammalian differentiation [RNA-Seq] 27 samples shares mammalian
- GSE273256 IgE plasma cells differentially regulate antibody secretion, ER stress and tissue-specific longevity relative to other isotypes 18 samples shares stress
- GSE269153 Alzheimer’s Disease Protective Allele of CLU Promotes Neuron Excitability, Neuron-glia Lipid Transfer and Astrocytic Lipid Droplets via neuronal CLU 18 samples shares transfer
- GSE275292 Tonicity drives maturation of the collecting ducts in the mammalian kidney 16 samples shares mammalian
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.