Simulating Neonatal Microglial Pan-Programmed Cell Death to Unlock Regenerative Potential in Adult Mice Spinal Cord Injury [RNA-seq]
RNA-seq (gene expression) · mouse · 21 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 21 samples: 6 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Neonatal-Inspired Reprogramming of Microglial Pan-Programmed Cell Death Enhances Regeneration in Adult Spinal Cord InjuryResearch (Washington, D.C.) · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE285895_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1206725 and SRA study SRP555378. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 21 samples.
How we read this: 6 replicated groups read from 21 sample titles; they account for 21 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8712266 Neonatal 3dpi1 Neonatal 3dpi
- GSM8712267 Neonatal 3dpi2 Neonatal 3dpi
- GSM8712268 Neonatal 3dpi3 Neonatal 3dpi
- GSM8712269 Neonatal 3dpi4 Neonatal 3dpi
- GSM8712270 Neonatal 7dpi1 Neonatal 7dpi
- GSM8712271 Neonatal 7dpi2 Neonatal 7dpi
- GSM8712272 Neonatal 7dpi3 Neonatal 7dpi
- GSM8712273 Adult Sham1 Adult Sham
- GSM8712274 Adult Sham2 Adult Sham
- GSM8712275 Adult Sham3 Adult Sham
- GSM8712276 Adult 1dpi1 Adult 1dpi
- GSM8712277 Adult 1dpi2 Adult 1dpi
- GSM8712278 Adult 1dpi3 Adult 1dpi
- GSM8712279 Adult 3dpi1 Adult 3dpi
- GSM8712280 Adult 3dpi2 Adult 3dpi
- GSM8712281 Adult 3dpi3 Adult 3dpi
- GSM8712282 Adult 3dpi4 Adult 3dpi
- GSM8712283 Adult 7dpi1 Adult 7dpi
- GSM8712284 Adult 7dpi2 Adult 7dpi
- GSM8712285 Adult 7dpi3 Adult 7dpi
- GSM8712286 Adult 7dpi4 Adult 7dpi
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- GSE247943 Cyclical macrophage plasticity provides periodic inflammatory and regenerative gene expression programs in cell cycle[RNA-Seq] 52 samples shares regenerative, rna-seq
- GSE275510 Deciphering Motor Dysfunction and Microglial Activation in mThy1-α-Synuclein Mice: A Comprehensive Study of Behavioral, Gene Experssion, and Methylation Changes [RNA-Seq] 20 samples shares microglial, rna-seq
- GSE282175 RNA-seq of retinal microglia and non-microglial retina cells in WT (Bmal1f/f) and microglial Bmal1-KO (Bmal1-mg/-mg) mice 18 samples shares microglial, rna-seq
- GSE307686 The Gain-of-Function TREM2-T96K Mutation Increases Risk for Alzheimer’s Disease by Impairing Microglial Function [scRNA-Seq] 15 samples shares microglial, rna-seq
- GSE337230 A transient neurodevelopmental microglial state governs cortical maturation and is disrupted by neonatal inflammation in mouse 13 samples shares microglial, neonatal
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.