A loss-of-function human ADAR variant activates innate immune response and triggers bowel inflammation

Direct links to NCBI, no account and no request form: the whole study as GSE290331_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1227498 and SRA study SRP565935. Searching any of these in the dataset finder brings you back here.

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• GSE235046 Innate immune and metabolic signaling retain damaged mitochondria at cell membranes for mitoxyperilysis 15 samples
• GSE293315 MRPGRX2 Antagonist Treatment Prevents Inflammation and Disease in a Mouse Model of Atopic Dermatitis Dataset 2 35 samples
• GSE263383 Unbiased niche labeling maps immune-excluded niche in bone metastasis 33 samples
• GSE326952 Semaglutide-induced Loss of Skeletal Muscle Mass is Blunted by Co-administration of Ketone Esters 13 samples
• GSE304391 Global identification of ER stress-regulated RNA binding Proteins in clonal pancreatic beta-cells, reveals an important role for DEAD-box helicase 3 X-linked (DDX3X) in the execution of the Unfolded Protein Response and the determination of cell fate. 12 samples
• GSE329539 Hypothalamic transcriptomic response to High-Fat Diet induced obesity: modulatory effects of Resveratrol, Curcumin, and Aged Garlic Extract. 12 samples
• GSE334497 TROP2/claudin program mediates immune exclusion to impede checkpoint blockade in breast cancer 10 samples

Search all mouse RNA-seq datasets in GEO →