The myth of postnatal lung maturation dominated by increased pulmonary blood flow and its clinical implications
RNA-seq (gene expression) · mouse · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 5 × p30_ipf vs 5 × p30_shamGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Neonatal pulmonary vascular remodeling induced by increased blood flow is associated with an antiviral-like immune signatureFrontiers in immunology · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE291221_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1232598 and SRA study SRP568303. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 2 replicated groups read from 10 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8831118 p30_ipf_1 p30_ipf
- GSM8831119 p30_ipf_2 p30_ipf
- GSM8831120 p30_ipf_3 p30_ipf
- GSM8831121 p30_ipf_4 p30_ipf
- GSM8831122 p30_ipf_5 p30_ipf
- GSM8831123 p30_sham_1 p30_sham
- GSM8831124 p30_sham_2 p30_sham
- GSM8831125 p30_sham_3 p30_sham
- GSM8831126 p30_sham_4 p30_sham
- GSM8831127 p30_sham_5 p30_sham
- GSE280388 Increased pulmonary blood flow leads to alveolar dysplasia at early postnatal developmental stage 10 samples shares postnatal, increased, pulmonary, blood
- GSE263678 Time‑course analysis of cisplatin induced AKI in preclinical models: implications for testing different sources of MSCs 32 samples shares implications, clinical
- GSE289897 Loss of Tbx4 Affects Postnatal Lung Development and Predisposes to Pulmonary Hypertension 12 samples shares postnatal, pulmonary
- GSE205438 RNA splicing controls organ-wide maturation of postnatal heart in mice 88 samples shares maturation, postnatal
- GSE213104 Gene expression profile at single cell level of Merkel cells from embryonic, neonatal and postnatal mouse skin 1057 samples shares postnatal
- GSE241089 First cleavage is a manifestation of the geometry of the unfertilized oocyte: implications for monozygotic twinning in mice. 219 samples shares implications
- GSE248780 ZFP57 is a regulator of postnatal growth and life-long health 120 samples shares postnatal
- GSE297245 Prenatal and postnatal effects of gestational immune activation on synaptic and neurodevelopmental pathways via epigenetic mechanisms (RNA-seq) 84 samples shares postnatal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.