GEO series
Salmonella typhimurium targets distal colonocytes to trigger infection
GSE291248
Mus musculus
Expression profiling by high throughput sequencing
10 samples
2025/12/09
GPL24247
Summary
To clarify how different intestinal cell types respond when facing the key intestinal pathogenic microorganism Salmonella, we conducted single-cell transcriptomic sequencing. The results revealed that a specific cluster of mature colonic epithelial cells was the most susceptible to infection. By describing the transcriptomic changes of this cluster of cells at different time points after infection, we further aimed to explain how this cluster of cells was affected by the infection.
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Paper (PMID 41277366) ↗
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