GEO series
Salmonella infection accelerates potential maturation of the intestinal epithelium
GSE278410
Mus musculus
Expression profiling by high throughput sequencing
32 samples
2024/12/17
GPL24247
Summary
Postnatal establishment of enteric metabolic, host-microbial and immune homeostasis is the result of precisely timed and tightly regulated developmental and adaptive processes. Here, we show that infection with the invasive enteropathogen Salmonella Typhimurium results in a Myd88-dependent accelerated maturation of the neonatal epithelium with premature appearance of antimicrobial, metabolic, developmental, and regenerative features of the adult tissue.
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Paper (PMID 39793046) ↗
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