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RNA-seq analysis of liver sinusoidal endothelial cells exposed to hydrostatic pressure stimulation

GSE291322 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/03/01 Platform GPL24247
Summary
Primary murine LSECs (mLSECs) were exposed to hydrostatic pressure (HP) stimulation. The expression of YAP/TAZ target genes such as CTGF and basement membrane-related genes such as COL4A1was upregulated in mLSECs exposed to HP stimulation.
Published in
Activation of the Integrin αV-YAP-CTGF Axis in Liver Sinusoidal Endothelial Cells Promotes Liver Fibrogenesis, Leading to Portal Hypertension and Liver Carcinogenesis in Congestive Hepatopathy
Kato S, Hikita H, Tsukamoto O et al. · Gastroenterology 2026 · PMID 41758081 · doi:10.1053/j.gastro.2025.11.014
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Also filed as BioProject PRJNA1232819 and SRA study SRP568526. Searching any of these in the dataset finder brings you back here.

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