GEO series
scRNA and TCR seq of CD8 TILs of WT and Card11 mutant mice(E134G/K215M)
GSE292543
Mus musculus
Expression profiling by high throughput sequencing
11 samples
2025/04/23
GPL34290
Summary
To investigate the impact of Card11 on TIL differentiation, we isolated TILs from B16-F10 tumors of WT mice, E134G mice, and K215M mice and performed scRNA seq. We also sorted tumor-infiltrating lymphocytes (TILs) from melanoma(B16-F10) of WT mice and conducted scRNA and scTCR sequencing. To further investigate the impact of Card11 on TCR clonal diversity, we sorted CD8 T cells from melanoma WT mice or K215M mice and performed scRNA and scTCR sequencing.
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