Nanoplastics induces Arrhythmia in Human Stem-cells derived Cardiomyocytes [mouse hearts]
RNA-seq (gene expression) · mouse · 21 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 21 samples: 21 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Nanoplastics induces arrhythmia in human stem-cells derived cardiomyocytesEcotoxicology and environmental safety · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE293469_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1244753 and SRA study SRP575699. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 12 samples read as cases, 9 as controls.
How we read this: Read from 21 sample titles: 21 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8882946 Control Mice 1 - Atrial Section
- GSM8882947 Control Mice 1 - Right Ventricular Section
- GSM8882948 Control Mice 1 - Left Ventricular Section
- GSM8882949 Control Mice 2 - Atrial Section
- GSM8882950 Control Mice 2 - Right Ventricular Section
- GSM8882951 Control Mice 2 - Left Ventricular Section
- GSM8882952 Control Mice 3 - Atrial Section
- GSM8882953 Control Mice 3 - Right Ventricular Section
- GSM8882954 Control Mice 3 - Left Ventricular Section
- GSM8882955 Nanoplastic Treated Mice 1 - Atrial Section
- GSM8882956 Nanoplastic Treated Mice 1 - Right Ventricular Section
- GSM8882957 Nanoplastic Treated Mice 1 - Left Ventricular Section
- GSM8882958 Nanoplastic Treated Mice 2 - Atrial Section
- GSM8882959 Nanoplastic Treated Mice 2 - Right Ventricular Section
- GSM8882960 Nanoplastic Treated Mice 2 - Left Ventricular Section
- GSM8882961 Nanoplastic Treated Mice 3 - Atrial Section
- GSM8882962 Nanoplastic Treated Mice 3 - Right Ventricular Section
- GSM8882963 Nanoplastic Treated Mice 3 - Left Ventricular Section
- GSM8882964 Nanoplastic Treated Mice 4 - Atrial Section
- GSM8882965 Nanoplastic Treated Mice 4 - Right Ventricular Section
- GSM8882966 Nanoplastic Treated Mice 4 - Left Ventricular Section
- GSE261940 Soluble ST2 induces cardiac contractile dysfunction by repressing mitochondrial electron transport chain genes in cardiomyocytes during fulminant myocarditis 20 samples shares cardiomyocytes, induces
- GSE291780 YAP Induces a Pro-Renewal Metabolic State in Cardiomyocytes: Cardiomyocyte-enriched Datasets 14 samples shares cardiomyocytes, induces
- GSE277680 Mitochondrial Ferritin Inhibition Aggravates Pacing-induced Ventricular Arrhythmias after Myocardial Infarction by Promoting Cardiomyocytes Ferroptosis 12 samples shares cardiomyocytes, arrhythmia
- GSE279575 Extracellular Vesicles Derived from Inflammatory Cardiomyocytes Mediate Macrophage Polarization and Alleviate Myocarditis via p38 MAPK Pathway 8 samples shares cardiomyocytes, derived
- GSE198735 Cardiac resident macrophage-derived legumain improves cardiac repair via promoting clearance and degradation of apoptotic cardiomyocytes after myocardial infarction 6 samples shares cardiomyocytes, derived
- GSE293319 Single cell RNA sequencing for non-cardiomyocytes in healthy, adaptive hypertrophy, and heart failure hearts of C57BL/6JJcl mice. 3 samples shares cardiomyocytes, hearts
- GSE296165 Single-cell RNA sequencing of non-cardiomyocytes obtained from wild-type mouse hearts 20 days after transverse aortic constriction or sham surgery 2 samples shares cardiomyocytes, hearts
- GSE49318 Genome-wide gene expression analysis of new cardiomyocytes (CMs) derived from resident c-kitpos endogenous cardiac stem cells (eCSCs) after myocardial injury by Isoproterenol (ISO) in mice. 9 samples shares cardiomyocytes, derived
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.