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Selective Janus kinase inhibitors exhibit different effects in murine bone marrow failure

GSE293645 Mus musculus Expression profiling by high throughput sequencing 15 samples 2026/03/11 GPL24247
Summary
We compared transcriptomes of bone marrow mononuclear cells (BMMNCs) and flow-sorted Lin-Sca-1+c-kit+ cells (LSK/HSPCs) from untreated bone marrow failure (BMF) mice and the mice treated with JAK inhibitors (JAKi): baricitinib (BAR), solcitinib (SOL), fedratinib (FED), and tofacitinib (TOF) at day 10 post BMF induction.
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NCBI GEO page ↗ Paper (PMID 41782810) ↗ {# Names what the click gives you. "Open in finder" meant nothing to a visitor who arrived from a search engine and has never seen the tool. #} Find more mouse RNA-seq datasets →
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