CircFKBP8(5S,6)-encoded protein promotes stress susceptibility in mice by downregulating dopamine D3 receptor expression and its downstream AMPK/mTOR/ULK1 autophagy signalling
RNA-seq (gene expression) · mouse · 3 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 3 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- circFKBP8(5S,6)-encoded protein promotes stress susceptibility in mice by down-regulating dopamine D3 receptor expression and its downstream AMPK/mTOR/ULK1 autophagy signalingGenes & diseases · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE294128_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1248427 and SRA study SRP577420. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 3 more — browse all 3 samples with per-sample file links →
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- GSE270825 AMPK promotes TFEB transcriptional activity through dephosphorylation at both mTORC1-dependent and -independent sites [dataset 2] 24 samples shares ampk, promotes
- GSE270824 AMPK promotes TFEB transcriptional activity through dephosphorylation at both mTORC1-dependent and -independent sites [dataset 1] 24 samples shares ampk, promotes
- GSE291140 AMPK suppresses multiple cell death pathways to sustain tumor-associated macrophage proportion and promotes tumor progression 12 samples shares ampk, promotes
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- GSE263411 Age-dependent autophagy impairment risks Alzheimer’s disease due to ULK1 reduction 12 samples shares ulk1, autophagy
- GSE284714 AMPK signaling downstream of adenosine 2A receptor represses Th17 cell pathogenicity through epigenetic and metabolic reprogramming. 15 samples shares ampk, downstream
- GSE284730 Astrocytic CREB in nucleus accumbens promotes susceptibility to chronic stress 39 samples shares susceptibility, promotes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.