Adipocyte-specific deletion of gp130 prevents ketogenic AQ1 diet–induced hepatic steatosis
RNA-seq (gene expression) · mouse · 23 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 23 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Adipocyte-specific deletion of gp130 prevents ketogenic diet-induced hepatic steatosisHepatology communications · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE294746_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1251539 and SRA study SRP579202. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 23 more — browse all 23 samples with per-sample file links →
- GSE273795 Pharmacological inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet 6 samples shares gp130, induced
- GSE283692 A ketogenic diet and voluntary exercise modify the sciatic nerve and gastrocnemius transcriptome in diet-induced obese mice 96 samples shares ketogenic, induced
- GSE293219 Adipocyte-specific Mlkl knockout mitigates obesity-induced metabolic dysfunction by enhancing mitochondrial functions. 36 samples shares adipocyte-specific, induced
- GSE248299 A ketogenic diet prevents metabolic switching durng time restricted feeding 15 samples shares ketogenic, prevents
- GSE297494 Total RNA transcriptomic profiling of mouse thoracic and abdominal perivascular adipose tissue of mice with an adipocyte-specific deletion of PRDM16 and flox control mice. 15 samples shares adipocyte-specific, deletion
- GSE333173 Ketogenic Diet Alleviates Acute Radiation-Induced Intestinal Injury through JAK2/STAT3/RORγt/IL-17A Signaling Pathway via Gut Microbiome 9 samples shares ketogenic, induced
- GSE298110 Adipocyte-Specific IGF1R Knockout Activates the β-Catenin/Apelin Axis to Combat Diet-Induced Obesity 6 samples shares adipocyte-specific, induced
- GSE297495 Total RNA transcriptomic profiling of mouse thoracic and abdominal perivascular adipose tissue of mice with an adipocyte-specific deletion of PRDM16 and flox control mice [snRNA-seq] 2 samples shares adipocyte-specific, deletion
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.