← BioTransfer GEO Dataset Finder
GEO series

Adipocyte-Specific IGF1R Knockout Activates the β-Catenin/Apelin Axis to Combat Diet-Induced Obesity

GSE298110 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/06/03 Platform GPL34290
Summary
Obesity, driven by complex genetic and environmental interactions, remains a global health crisis with limited therapeutic options. The insulin-like growth factor 1 receptor (IGF1R) plays dual roles in metabolism and growth, but its tissue-specific functions in adipose biology are controversial. This study investigates how adipose-specific IGF1R knockout impacts systemic metabolism under high-fat diet (HFD) stress and explores the underlying mechanisms.
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE298110_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1268372 and SRA study SRP588450. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.