Utx (Kdm6a) promotes differentiation non-catalytically in somatic self-renewing epithelia [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 17 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 17 samples: 17 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- UTX (KDM6A) promotes differentiation noncatalytically in somatic self-renewing epitheliaProceedings of the National Academy of Sciences of the United States of America · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE294851_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1251689 and SRA study SRP579124. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 17 sample titles: 17 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8927035 X1244 UTX
- GSM8927036 X1245 UTX
- GSM8927037 X1249 UTX
- GSM8927038 X1247 UTX
- GSM8927039 X1250 UTX
- GSM8927040 X1258 UTX
- GSM8927041 X1245 H3K27ac
- GSM8927042 X1249 H3K27ac
- GSM8927043 X1247 H3K27ac
- GSM8927044 X1250 H3K27ac
- GSM8927045 X1258 H3K27ac
- GSM8927046 X1244 Input
- GSM8927047 X1245 Input
- GSM8927048 X1249 Input
- GSM8927049 X1247 Input
- GSM8927050 X1250 Input
- GSM8927051 X1258 Input
- GSE237390 Loss of Kmt2c or Kmt2d drives brain metastasis via KDM6A-dependent upregulation of MMP3 [ChIP-seq] 54 samples shares kdm6a, chip-seq
- GSE303502 EZH2 directs breast cancer progression through the modulation of epithelial cellular plasticity [ChIP-Seq] 16 samples shares epithelia, chip-seq
- GSE327565 Sustained Yap/Taz activation promotes aberrant alveolar epithelial cell differentiation and drives persistent fibrotic remodeling 14 samples shares epithelia, promotes
- GSE271272 Fibroblast-derived osteoglycin promotes alveolar epithelial cell repair 32 samples shares epithelia, promotes
- GSE264369 Fatty acid oxidation downregulation in alveolar epithelial 2 cells promotes acute lung injury in obesity 18 samples shares epithelia, promotes
- GSE317252 Enhanced mitophagy promotes lung repair and regeneration by restoring epithelial metabolic fitness [RNA-Seq] 16 samples shares epithelia, promotes
- GSE306861 ALDH2 inhibition reprograms tubular epithelial cell metabolism and promotes renal injury susceptibility 8 samples shares epithelia, promotes
- GSE342447 TH-positive pulmonary nerve fiber-epithelial interaction promotes adipose thermogenesis in male mice [C22_RNA-seq] 4 samples shares epithelia, promotes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.