Miconazole attenuates LPS-induced lung inflammation by modulating alveolar macrophage polarization through the regulation of lipid metabolism
Single-cell RNA-seq · mouse · 2 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart. Read from the summary: GEO's own type field only says 'expression profiling by sequencing', so confirm it in the paper.
- Organism
- Mus musculus (mouse)
- Samples
- 2 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Miconazole attenuates LPS-induced lung inflammation by modulating alveolar macrophage polarization via promoting lipid metabolic reprogrammingInflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE295628_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1255311. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 2 more — browse all 2 samples with per-sample file links →
- GSE202753 DsbA-L deficiency attenuates LPS-induced acute kidney injury via NF-κB/AP-1 regulation of macrophage polarization 13 samples shares polarization, lps-induced, attenuates, macrophage
- GSE244502 IBR1: A Novel Endogenous dsRNA Binding to the Helicase Domain of IFIH1 and Its Role in LPS-induced IFIH1 Activation and Macrophage M1 Polarization in ARDS [RNA-seq] 10 samples shares polarization, lps-induced, macrophage
- GSE235016 RNA-seq revealed the anti-pyroptotic effect of suramin by suppressing NLRP3/caspase-1/GSDMD pathway in LPS-induced MH-S alveolar macrophages 9 samples shares lps-induced, macrophage, alveolar
- GSE247177 IBR1: A Novel Endogenous dsRNA Binding to the Helicase Domain of IFIH1 and Its Role in LPS-induced IFIH1 Activation and Macrophage M1 Polarization in ARDS 20 samples shares polarization, lps-induced, macrophage
- GSE283748 Skatole attenuates osteoarthritis by protecting chondrocytes and mediating macrophage repolarization through regulating the NFκB/MAPK signaling pathway and metabolic reprogramming II 10 samples shares polarization, attenuates, macrophage
- GSE249577 Research on the Mechanism of PTEN Mediated tumor-associated macrophages (TAMs) Polarization 46 samples shares polarization, macrophage
- GSE283547 Suppression of Notch during efferocytosis prevents macrophages inflammatory polarization [RNA-seq.HumanMouse] 40 samples shares polarization, macrophage
- GSE325329 Transcriptomic profiling of macrophages that phagocytosed apoptotic Treg or conventional CD4⁺ T (Tconv) cells under different polarization conditions [RNA-Seq] 28 samples shares polarization, macrophage
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.