Total RNA-seq of mouse olfactory epithelium in response to single odorants and binary mixtures

Total RNA was extracted from olfactory epithelium tissues of mice exposed to single odorants (acetophenone, decanal, octanal, and cis-3-hexenol) or binary mixtures (acetophenone–decanal and octanal–cis-3-hexenol). The extracted RNA was subjected to high-throughput sequencing to profile genome-wide transcriptional changes across all cell types of the olfactory epithelium following odor stimulation. This dataset provides a baseline reference for comparing odor-induced gene expression programs in the olfactory epithelium with transcriptomic profiles obtained from odor-activated neuronal populations enriched by pS6 immunoprecipitation.