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Reduction of neuronal activity mediated by blood-vessel regression in the adult brain

GSE296574 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2025/05/08 Platform GPL19057
Summary
To explore the role of brain vascular TAK1 and its functional mechanism , we performed RNA-seq between Cdh5-CreER::Tak1fl/fl mice and their littermate control mice at the age of 12–14 weeks to identify the expression of some unique genes and possible pathway related to the function of brain vascular TAK1. We confirmed the role of brain vascular TAK1 contributed to Glutamate neuronal survival and activity.
Published in
Reduction of neuronal activity mediated by blood-vessel regression in the adult brain
Gao X, Chen XJ, Ye M et al. · Nature communications 2025 · PMID 40595484 · doi:10.1038/s41467-025-60308-0
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Also filed as BioProject PRJNA1259991 and SRA study SRP583648. Searching any of these in the dataset finder brings you back here.

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