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Elucidating the impact of chemotherapy on skeletal progenitors [RNA-seq Osteoblast]

GSE296757 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2026/06/15 Platform GPL24247
Summary
Mice receiving cyclic doxorubicin (DOX) treatment exhibited long-term skeletal defects. Lineage tracing experiments revealed loss of osteogenesis from bone marrow mesenchymal stem and progenitor cells. We performed molecular characterization on MSPCs to understand the mechanisms underying MSPC dysfunction folloiwng DOX treatment.
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Direct links to NCBI, no account and no request form: the whole study as GSE296757_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1261011 and SRA study SRP584196. Searching any of these in the dataset finder brings you back here.

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