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Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3' UTRs and Near Stop Codons

GSE29714 Mus musculus; Homo sapiens Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing 11 samples Submitted 2012/05/17 Platform GPL11002Platform GPL13112Platform GPL11154
Summary
Here, we use a novel technique for locating regions of N6-adenosine methylation (m6A) throughout the transcriptome and present a profile of m6A sites in the mouse brain. Our use of methylated RNA immunoprecipitation combined with RNA-seq (MeRIP-Seq) identifies thousands of RNAs which contain m6A sites. In addition, we find that regions of m6A formation are particularly enriched near stop codons, which might provide clues into the potential funciton of this highly prevalent RNA modificaiton.
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Also filed as BioProject PRJNA141085 and SRA study SRP007335. Searching any of these in the dataset finder brings you back here.

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