Gpc3 Selectively Suppresses Subcutaneous Adipogenesis in Diet-Induced Obesity
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 12 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE298345_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1269000 and SRA study SRP588284. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 12 sample titles: 12 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9012222 iWAT_SVF_18CD, scRNA seq
- GSM9012223 iWAT_SVF_18HFD, scRNA seq
- GSM9024548 eWAT_SVF_12CD, scRNA seq
- GSM9024549 eWAT_SVF_12HFD, scRNA seq
- GSM9024550 eWAT_SVF_18CD, scRNA seq
- GSM9024551 eWAT_SVF_18CD_2, scRNA seq
- GSM9024552 eWAT_SVF_18HFD, scRNA seq
- GSM9024553 eWAT_SVF_Switch, scRNA seq
- GSM9024554 iWAT_SVF_12CD, scRNA seq
- GSM9024555 iWAT_SVF_12HFD, scRNA seq
- GSM9024556 iWAT_SVF_18CD_2, scRNA seq
- GSM9024557 iWAT_SVF_Switch, scRNA seq
- GSE302447 A multi-functional oral small molecule targeting energy and lipid metabolism as a treatment for diet-induced obesity 67 samples shares diet-induced, obesity
- GSE262523 Diet-Induced Obesity Disrupts Sexually Dimorphic Gene Expression in Liver and Adipose Tissue in Mice 48 samples shares diet-induced, obesity
- GSE312093 Ramulus Mori (Sangzhi) Alkaloids Attenuate Diet-Induced Obesity by Promoting White Adipose Browning and Enhancing Brown Fat Thermogenesis 43 samples shares diet-induced, obesity
- GSE303998 Whole body MondoA deletion protects against diet-induced obesity through uncontrolled multi-organ substrate utilization and futile cycling 40 samples shares diet-induced, obesity
- GSE252343 Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity 34 samples shares diet-induced, obesity
- GSE315007 Sex- and hepatocyte Pparg-dependent hepatic effects of a high fat diet containing 60% kcal from fat and 2% cholesterol, which was supplemented with 10% fructose in the drinking water (HFC+Fr) to induce diet-induced obesity in male and female mice. 30 samples shares diet-induced, obesity
- GSE298120 Succinate Modulation as a Novel Mechanism Underlying the Effects of Intermittent Fasting on Brain Function and Metabolism in Diet-Induced Obesity 29 samples shares diet-induced, obesity
- GSE285121 The fungicide propiconazole induces hepatic steatosis and activates PXR in a mouse model of diet-induced obesity 24 samples shares diet-induced, obesity
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.