← BioTransfer GEO Dataset Finder
GEO series

Estrogen receptor beta action in mouse granulosa cells in response to LH surge [ERb]

GSE299767 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 5 samples Submitted 2026/05/08 Platform GPL19057
Summary
Estrogen signalling is crucial for follicle development, ovulation, ovarian identity maintenance and female fertility. The canonical pathway for estrogen signalling is through the activation of estrogen receptor alpha (ERa) and beta (ERb), both of which are present in ovarian granulosa cells. To determine the involvement of each estrogen receptor in ovarian functions across folliculogenesis and ovulation, we characterised the chromatin binding profile of ERb and ERb in mouse granulosa cells in response to in vivo LH stimulus.
Published in
Estrogen receptor alpha and beta chromatin interactions govern ovarian folliculogenesis but dissipate during ovulation
Dinh DT, McPhee TR, Foot NJ et al. · Endocrinology 2026 · PMID 42057691 · doi:10.1210/endocr/bqag052
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE299767_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 5 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1276470 and SRA study SRP591859. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 5 more — browse all 5 samples with per-sample file links →

Similar datasets

Search all mouse ChIP / ATAC / CUT&Tag datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.