GEO series
Single-embryo and single-blastomere RNA-seq analysis of 2-cell and 4-cell mouse embryos
GSE300864
Mus musculus
Expression profiling by high throughput sequencing
39 samples
2026/06/01
GPL24247
Summary
Understanding how the first cell fate decisions arise in the mammalian embryo remains a central question in developmental biology. While lineage segregation becomes morphologically apparent at the 16-cell stage, increasing evidence suggests that molecular asymmetries emerge much earlier. Here, we systematically profile the transcriptome of whole embryo and individual blastomere of mouse embryos at 2-cell and 4-cell stage using SMART-Seq2.
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