Single-embryo RNA-seq analysis in LAD disrupted 2-cell embryos.
RNA-seq (gene expression) · mouse · 87 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 87 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The establishment of nuclear organization in mouse embryos is orchestrated by multiple epigenetic pathwaysCell · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE278720_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1168526 and SRA study SRP536502. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 87 more — browse all 87 samples with per-sample file links →
- GSE300864 Single-embryo and single-blastomere RNA-seq analysis of 2-cell and 4-cell mouse embryos 39 samples shares 2-cell, single-embryo, rna-seq, embryos
- GSE222656 RNA-seq and Cut & Tag analyses of mouse 2-cell embryos in which lamin B1 dissociation from the nuclear envelope is inhibited 40 samples shares 2-cell, rna-seq, embryos
- GSE301477 RNA-seq analysis of arterial smooth muscle cells (ASMCs) isolated from the lung, heart, aorta, stomach, intestine, kidney and bladder 22 samples shares lad, rna-seq
- GSE301480 RNA-seq analysis of non-vascular smooth muscle cells (NVSMCs) isolated from the lung, intestine and bladder 8 samples shares lad, rna-seq
- GSE234326 Rosiglitazone and Trametinib to treat basal bladder tumors [RNA-Seq] 62 samples shares lad, rna-seq
- GSE282840 N6-methyladenosine modulate second cell fate decision by enhancing mRNA stability of pivotal transcription factors during primitive endoderm development [EPSC_RNA-seq] 46 samples shares lad, rna-seq
- GSE247082 Lysosomal catabolic activity governs the exit of the murine totipotent 2-cell state by silencing early-embryonic retrotransposons [RNA-seq] 30 samples shares 2-cell, rna-seq
- GSE33923 2C::tomato ES cells, 2-cell embryos and wild type oocytes 16 samples shares 2-cell, embryos
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.