Distinct Hepatocarcinogenesis Results From Alcohol and High Fat Diet in Diabetic Mice
RNA-seq (gene expression) · mouse · 22 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 22 samples: 22 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE302261_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1289747 and SRA study SRP599904. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 22 sample titles: 22 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9100565 30805_7-MASH_T
- GSM9100566 30806_8-MASH_A
- GSM9100567 30809_11-MASH_T
- GSM9100568 30810_12-MASH_A
- GSM9100569 30818_s7-MASH_T
- GSM9100570 30819_s8-MASH_A
- GSM9100571 30820_s9-MASH_T
- GSM9100572 30821_s10-MASH_A
- GSM9100573 30799_1-ASH_T
- GSM9100574 30800_2-ASH_A
- GSM9100575 30801_3-ASH-T
- GSM9100576 30802_4-ASH-A
- GSM9100577 30803_5-ASH-T
- GSM9100578 30804_6-ASH-A
- GSM9100579 30814_s3-ASH-T
- GSM9100580 30815_s4-ASH-A
- GSM9100581 30816_s5-ASH-T
- GSM9100582 30817_s6-ASH-A
- GSM9512231 MetALD
- GSM9512232 MASH
- GSM9512233 30807_9-MetALD_T
- GSM9512234 30808_10-MetALD_A
- GSE192687 Single-cell RNAseq analysis of renal endothelial cells in murine diabetic nephropathy 5464 samples shares diabetic
- GSE235792 Body weight at weaning is the main predictor for diabetic phenotype in male TallyHo/JngJ mice 87 samples shares diabetic
- GSE329024 Distinct HPO axis responses to chronic unpredictable stress in young versus adult female mice 63 samples shares distinct
- GSE254704 Skeletal muscle cystathionine γ-lyase deficiency promotes obesity and insulin resistance and results in hyperglycemia and skeletal muscle injury upon HFD in mice 32 samples shares results
- GSE285966 Empagliflozin restores cardiac function in obese-diabetic HFpEF mice butfurther alters gene expression 30 samples shares diabetic
- GSE228960 Bulk RNA-Seq from kidneys of uninephrectomized db/db mice as a model of severe diabetic kidney disease 28 samples shares diabetic
- GSE292224 Distinct molecular mechanisms of stress habituation in the mouse hippocampus [bulk RNA-seq] 190 samples shares distinct
- GSE295612 APOE4 expression causes distinct effects on meningeal immunity, brain lipid composition, and cognition in male and female mice 16 samples shares distinct
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.