MicroRNA210 regulated brain pericyte dysfunction exacerbates hypoxic-ischemic brain injury in neonatal mice
RNA-seq (gene expression) · mouse · 15 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 15 samples: 10 distinct titles, 2 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- MicroRNA210 regulated brain pericyte dysfunction exacerbates hypoxic-ischemic brain injury in neonatal miceFluids and barriers of the CNS · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE312452_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1373341 and SRA study SRP651198. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 15 sample titles: 10 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9346124 WT-Sham1
- GSM9346125 WT-Sham2
- GSM9346126 WT-Sham3
- GSM9346127 KO-Sham1
- GSM9346128 KO-Sham3
- GSM9346129 KO-Sham4
- GSM9346130 KO-Sham6
- GSM9346131 WT-HI1_24 h
- GSM9346132 WT-HI2_24 h
- GSM9346133 WT-HI4_24 h
- GSM9346134 WT-HI5_24 h
- GSM9346135 KO-HI1_24 h
- GSM9346136 KO-HI2_24 h
- GSM9346137 KO-HI3_24 h
- GSM9346138 KO-HI4_24 h
- GSE232098 Innate immune memory after brain injury drives inflammatory cardiac dysfunction 20 samples shares dysfunction, injury, brain
- GSE302721 Allopregnanolone is neuroprotective in hypoxic-ischemic injury of the immature brain 10 samples shares hypoxic-ischemic, injury, brain
- GSE297195 Age-dependent Transcriptional and Circuit Alterations in the brain Underlie Post-Anesthesia Neurobehavioral Dysfunction 66 samples shares dysfunction, brain
- GSE291921 Linking trajectories of cerebrovascular remodeling and dysfunction to cross-species brain vessel transcriptome in Alzheimer’s disease 24 samples shares dysfunction, brain
- GSE284451 Ceramides Drive Mitochondrial Dysfunction and Tubular Injury in AKI 16 samples shares dysfunction, injury
- GSE302342 Lack of cortistatin drives neuroimmune and vascular dysfunction in brain ischemia 14 samples shares dysfunction, brain
- GSE245987 Vascular endothelial S1PR2 aggravates cardiac ischemia/reperfusion injury through triggering mitochondrial dysfunctions and endothelial pyroptosis via RHO/ROCK1/DRP1/NLRP3 pathway [heart] 4 samples shares dysfunction, injury
- GSE294772 Single-Cell Epigenomics Uncovers Heterochromatin Instability and Transcription Factor Dysfunction during Mouse Brain Aging [snATAC-Seq] [10X Multiome] 142 samples shares dysfunction, brain
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.