Regional Conservation and Transcriptional Regulation of Tumor-Associated Genes by macroH2A1 Deposition in Mammalian Cells
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 12 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 12 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Regional Conservation and Transcriptional Regulation of Tumor-Associated Genes by macroH2A1 Deposition in Mammalian CellsBiomolecules · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE303932_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1298254 and SRA study SRP604298. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 12 sample titles: 12 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9138344 ARPE-19, G1/S, macroH2A1 (input)
- GSM9138345 ARPE-19, G1/S, macroH2A1, Rep1 (Chip)
- GSM9138346 ARPE-19, G1/S, macroH2A1, Rep2 (Chip)
- GSM9138347 ARPE-19, Meta, macroH2A1 (input)
- GSM9138348 ARPE-19, Meta, macroH2A1, Rep1 (Chip)
- GSM9138349 ARPE-19, Meta, macroH2A1, Rep2 (Chip)
- GSM9138350 HeLa, G1/S, macroH2A1 (input)
- GSM9138351 HeLa, G1/S, macroH2A1, Rep1 (Chip)
- GSM9138352 HeLa, G1/S, macroH2A1, Rep2 (Chip)
- GSM9138353 HeLa, Meta, macroH2A1 (input)
- GSM9138354 HeLa, Meta, macroH2A1, Rep1 (Chip)
- GSM9138355 HeLa, Meta, macroH2A1, Rep2 (Chip)
- GSE331503 Lactylation of histone variant MacroH2A1 at K134 regulates osteogenic differentiation of bone marrow mesenchymal stem cells [ATAC] 2 samples shares macroh2a1
- GSE272267 Human cytomegalovirusinduces neuronal geneexpression to promote virionmaturationin macroH2A1-dependent manner 36 samples shares macroh2a1
- GSE291064 Human cytomegalovirus induces neuronal gene expression to promote virion maturation in macroH2A1-dependent manner 15 samples shares macroh2a1
- GSE331389 Lactylation of histone variant MacroH2A1 at K134 regulates osteogenic differentiation of bone marrow mesenchymal stem cells 8 samples shares macroh2a1
- GSE276400 Nuclear compartmentalization of PD-L1 suppresses tumorigenesis and overcomes immunocheckpoint therapy resistance via histone macroH2A1 phosphorylation 6 samples shares macroh2a1
- GSE262583 Transcriptional condensates enrich phosphorylated PRMT2 to stimulate H3R8me2a deposition and hypoxic response in cancers- Cut&tag 10 samples shares deposition
- GSE278642 Growth signaling promotes H2A.Z deposition by SRCAP to sustain somatic tissue regeneration [ChIP-Seq] 30 samples shares deposition
- GSE282179 SPT6 Regulates H3K14Ac Deposition in Mouse Embryonic Stem Cells [ChIP-seq-HEK293T] 24 samples shares deposition
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.