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Transcriptomic response to corticosterone treatment in murine osteoblasts.

GSE304562 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/03/27 Platform GPL24247
Summary
To assess the transcriptomic response to corticosterone treatment in osteoblasts, we treated differentiated MC3T3 osteoblasts cells with 100 nM corticosterone for 24 hours. Comprehensive RNA-seq analysis was performed to identify differentially expressed genes and pathways associated with glucocorticoid receptor activation, osteoblast activity, and inflammatory responses. This study provides insights into the molecular mechanisms underlying corticosterone-mediated suppression of FGF23 expression and its broader effects on bone metabolism.
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Direct links to NCBI, no account and no request form: the whole study as GSE304562_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1301791 and SRA study SRP606681. Searching any of these in the dataset finder brings you back here.

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