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Osteocytic FSH inhibition rescues bone mass and boosts fracture healing in ovariectomized mice

GSE305679 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/12/01 Platform GPL24247
Summary
RNA-seq of femoral cortical bone from osteocyte-specific Fshr knockout mice (Dmp1-CreERT; Fshrfl/fl) identifies PI3K/Akt pathway activation and enhanced osteoblast-osteoclast coupling underlying increased bone mineralization and accelerated fracture repair in ovariectomized mice.
Published in
Osteocytic FSH inhibition rescues bone mass and boosts fracture healing in ovariectomized mice
Liu Z, Sun M, Zhou H et al. · Life sciences 2026 · PMID 41317982 · doi:10.1016/j.lfs.2025.124121
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Also filed as BioProject PRJNA1307458 and SRA study SRP609923. Searching any of these in the dataset finder brings you back here.

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