Engineered thoracic spinal cord organoids for transplantation after spinal cord injury
RNA-seq (gene expression) · human · 26 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 26 samples: 7 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Engineered thoracic spinal cord organoids for transplantation after spinal cord injuryNature biomedical engineering · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE305911_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1307158 and SRA study SRP609491. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 23 samples.
How we read this: 7 replicated groups read from 26 sample titles; they account for 23 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9187667 spinal cord with enTsOrg_7wpi
- GSM9187668 spinal cord with sOrg_7wpi
- GSM9187669 enTsOrg-sOrg_3w-ST-seq
- GSM9187670 iPSC_rep1 iPSC
- GSM9187671 iPSC_rep2 iPSC
- GSM9187672 iPSC_rep3 iPSC
- GSM9187673 enTsOrg_2w_rep1 enTsOrg_2w
- GSM9187674 enTsOrg_2w_rep2 enTsOrg_2w
- GSM9187675 enTsOrg_2w_rep3 enTsOrg_2w
- GSM9187676 enTsOrg_3w_rep1 enTsOrg_3w
- GSM9187677 enTsOrg_3w_rep2 enTsOrg_3w
- GSM9187678 enTsOrg_3w_rep3 enTsOrg_3w
- GSM9187679 enTsOrg_8w_rep1 enTsOrg_8w
- GSM9187680 enTsOrg_8w_rep2 enTsOrg_8w
- GSM9187681 enTsOrg_8w_rep3 enTsOrg_8w
- GSM9187682 enTsOrg_8w_rep4 enTsOrg_8w
- GSM9187683 sOrg_2w_rep1 sOrg_2w
- GSM9187684 sOrg_2w_rep2 sOrg_2w
- GSM9187685 sOrg_2w_rep3 sOrg_2w
- GSM9187686 sOrg_3w_rep1 sOrg_3w
- GSM9187687 sOrg_3w_rep2 sOrg_3w
- GSM9187688 sOrg_3w_rep3 sOrg_3w
- GSM9187689 sOrg_8w_rep1 sOrg_8w
- GSM9187690 sOrg_8w_rep2 sOrg_8w
- GSM9187691 sOrg_8w_rep3 sOrg_8w
- GSM9187692 sOrg_8w_rep4 sOrg_8w
- GSE261159 Gene expression dynamics of branching morphogenesis in pancreatic cancer organoids (2) 181 samples shares organoids
- GSE185152 The RANBP2/Importin-7-FOXO1 axis provides superior cold protection to aid islet transplantation 89 samples shares transplantation
- GSE305923 exoWNT3A/RSPO1 improves HE to LPC differentiation, hepatic organoids growth, and different acute and chronic liver injuries. 72 samples shares organoids
- GSE276838 Glioblastoma-cortical organoids recapitulate cell state heterogeneity and intercellular transfer 29 samples shares organoids
- GSE226195 Signaling basis of gastric epithelial cell differentiation revealed by human and mouse organoids [RNA-Seq] 26 samples shares organoids
- GSE327614 Early cell autonomous and niche-mediated alveolar epithelial response to influenza infection in primary lung organoids 24 samples shares organoids
- GSE224475 ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution (human+murine organoids subset) 21 samples shares organoids
- GSE276320 Chromodomain protein CDYL confers forebrain identity to human cortical organoids by inhibiting neuronatin [RNA-seq] 18 samples shares organoids
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.