GEO series
Bulk RNASeq of Stromal Subsets in Wildtype and GD T cell-deficent Mice in Biomaterial Implant Fibrosis
GSE306146
Mus musculus
Expression profiling by high throughput sequencing
16 samples
2026/03/11
GPL24247
Summary
The main objective of this study is to investigate the role of gamma delta (GD) T cells on stromal cell behavior in chronic tissue injury and foreign body response (synthetic polycaprolactone PCL implant). We isolate key stromal cell populations (Fibroblasts and Endothelial Cells) from fibrotic PCL implants of wildtype (WT) and GD-deficient (GDKO) mice using FACS and compare their transcriptomic profile using bulk RNA-sequencing.
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